Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease.
Identifieur interne : 000A74 ( Main/Exploration ); précédent : 000A73; suivant : 000A75Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease.
Auteurs : Natalja Funk [Allemagne] ; Peter Wieghofer ; Sabrina Grimm ; Richard Schaefer ; Hans-Jörg Bühring ; Thomas Gasser ; Saskia BiskupSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2013.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Female, Flow Cytometry, Hematopoietic Stem Cells (immunology), Hematopoietic Stem Cells (physiology), Humans, Male, Middle Aged, Monocytes (immunology), Monocytes (physiology), Parkinson Disease (genetics), Parkinson Disease (pathology), Protein-Serine-Threonine Kinases (genetics), Receptors, CCR2 (metabolism), Statistics, Nonparametric.
- MESH :
- chemical , genetics : Protein-Serine-Threonine Kinases.
- genetics : Parkinson Disease.
- immunology : Hematopoietic Stem Cells, Monocytes.
- chemical , metabolism : Receptors, CCR2.
- pathology : Parkinson Disease.
- physiology : Hematopoietic Stem Cells, Monocytes.
- Adult, Aged, Aged, 80 and over, Female, Flow Cytometry, Humans, Male, Middle Aged, Statistics, Nonparametric.
Abstract
Emerging evidence has highlighted the pivotal role of the immune system in neurodegenerative diseases. This study investigated the impact of progressive neurodegeneration on the differentiation and development of hematopoietic stem cells in the peripheral blood of Parkinson's patients.
DOI: 10.1002/mds.25300
PubMed: 23401086
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Emerging evidence has highlighted the pivotal role of the immune system in neurodegenerative diseases. This study investigated the impact of progressive neurodegeneration on the differentiation and development of hematopoietic stem cells in the peripheral blood of Parkinson's patients.</div>
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<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Funk, Natalja" sort="Funk, Natalja" uniqKey="Funk N" first="Natalja" last="Funk">Natalja Funk</name>
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